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DeCS
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Descriptor English:
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Dosage Compensation, Genetic
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Descriptor Spanish:
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compensación de dosis genética
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Descriptor Portuguese:
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Compensação de Dosagem (Genética)
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Synonyms English:
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Compensation, Dosage (Genetics)
Compensation, Gene Dosage
Compensation, Genetic Dosage
Dosage Compensation (Genetics)
Dosage Compensation, Gene
Gene Dosage Compensation
Gene Dosage Compensations
Genetic Dosage Compensation
Genetic Dosage Compensations
Hypertranscription, X Chromosome
Hypertranscription, X-Chromosome
X Chromosome Hypertranscription
X-Chromosome Hypertranscription
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Tree Number:
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G05.308.203.249
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Definition English:
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Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female. |
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Indexing Annotation English:
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do not confuse with GENE DOSAGE
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History Note English:
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2006 (1982)
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Allowable Qualifiers English:
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Record Number:
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27989
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Unique Identifier:
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D004303
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Occurrence in VHL:
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Similar:
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DeCS
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